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Genome Biol. 2009;10(6):222. doi: 10.1186/gb-2009-10-6-222. Epub 2009 Jun 5.

Sequence patches on MAPK surfaces define protein-protein interactions.

Author information

  • 1Department of Pharmacology and Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7365, USA. glj@med.unc.edu

Abstract

Recent studies on the modularity of mitogen-activated protein kinases show how redesigning 'surface patches' on a protein can change the topology of a signaling network.

PMID:
19519955
[PubMed - indexed for MEDLINE]
PMCID:
PMC2718487
Free PMC Article

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