University of Basel, Institute of Zoology and Evolutionary Biology, Vesalgasse 1, Basel CH-4051, Switzerland. dupasquier@dial.eunet.ch
A novel diversified multigene family of tripartite-motif (TRIM) intracellular receptors with putative antiviral activity has been identified in teleost fish and published in BMC Biology. The history of these receptors involves ancient linkage to paralogs of the major histocompatibility complex, and the family has invertebrate precursors.