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Acta Neurol Scand. 2009 Nov;120(5):295-9. doi: 10.1111/j.1600-0404.2009.01183.x. Epub 2009 Jun 11.

Long-term outcome after surgery for Chiari I malformation.

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  • 1Hydrocephalus Unit, Institute of Clinical Neuroscience, The Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden.

Abstract

OBJECTIVE:

To examine the long-term effects of suboccipito-cervical decompression on an intention-to-treat basis in patients with Chiari I malformation (CMI).

PATIENTS AND METHODS:

Twenty-four consecutive patients, 14 females and 10 males with a median age of 26 years, underwent decompressive surgery for CMI during 1998-2006. All patients were contacted by an independent examiner and asked to complete a questionnaire regarding headache, other neurological symptoms and negative impact of the disease on the daily life before and after surgery. The median follow-up time after surgery was 3.2 years (range 1.7-9.2 years). Twenty-three patients (96%) completed the questionnaire.

RESULTS:

On an intention-to-treat basis there was an improvement in headache in 75%, decreased associated neurological symptoms in 88% and less negative impact on daily life in 75% of the 24-operated patients.

CONCLUSIONS:

More than three-quarters of the patients still considered their situation improved at long-term follow-up after surgery. These results support surgical intervention in symptomatic Chiari I patients.

[PubMed - indexed for MEDLINE]
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