Source
Key laboratory of Bioactive Substances and Resources of Chinese Herbal Medicine (Ministry of Education), Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Abstract
OBJECTIVE:
To isolate and identify chemical constituents from Phellodendron chinense.
METHODS:
Chemical constituents were isolated by silica gel and Sephadex LH-20 column chromatography. The structures of the isolated compounds were determined by spectral means.
RESULTS:
Ten compounds were isolated and identified as berberine (1), caffeic acid ethyl ester (2), iso-vanillin (3), ferulic acid (4), (+/-)-5,5'-dimethoxylariciresinol (5), Methyl beta-orsellinate (6), gamma-fagirine (7), (+/-)-Lyoniresinol (8), beta-sitosterol (9), stigmasterine (10).
CONCLUSIONS:
Compounds 2-6 are isolated and identified from this genus for the first time.