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Cell. 2009 May 29;137(5):800-2. doi: 10.1016/j.cell.2009.05.013.

FOXP2 and Human Cognition.

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  • 1Cognitive and Linguistic Sciences, Brown University, Providence, RI 02912, USA.


Using a mouse model, Enard et al. (2009) show that the human form of the FOXP2 gene increases synaptic plasticity and dendrite connectivity in the basal ganglia. These results partly explain the enhanced capability of cortico-basal ganglia circuits in the human brain that regulate critical aspects of language, cognition, and motor control.

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