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J Mol Evol. 2009 Jul;69(1):1-9. doi: 10.1007/s00239-009-9248-z. Epub 2009 Jun 2.

A comparison among the models proposed to explain the origin of the tRNA molecule: A synthesis.

Author information

  • Institute of Genetics and Biophysics, 'Adriano Buzzati Travers,' CNR, Naples, Napoli, Italy. digiulio@igb.cnr.it

Abstract

A comparison is made among all the models proposed to explain the origin of the tRNA molecule. The conclusion reached is that, for the model predicting that the tRNA molecule originated after the assembly of two hairpin-like structures, molecular fossils have been found in the half-genes of the tRNAs of Nanoarchaeum equitans. These might be the witnesses of the transition stage predicted by the model through which the evolution of the tRNA molecule passed, thus providing considerable corroboration for this model.

PMID:
19488799
[PubMed - indexed for MEDLINE]
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