Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
DNA Repair (Amst). 2009 Sep 2;8(9):1089-100. doi: 10.1016/j.dnarep.2009.04.010. Epub 2009 May 30.

Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks.

Author information

  • 1Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH-4058 Basel, Switzerland.

Abstract

DNA damage during replication requires an integration of checkpoint response with replication itself and distinct repair pathways, such as replication pausing, recombination and translesion synthesis. Here we focus on recent advances in our understanding of how protein posttranslational modifications contribute to the maintenance of fork integrity. In particular, we examine the role of histone modifications and chromatin remodeling complexes in this process.

PMID:
19482523
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk