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Nat Rev Cardiol. 2009 Jun;6(6):391-2. doi: 10.1038/nrcardio.2009.76.

Coronary artery disease: Platelet activity: an obstacle for successful PCI.

Abstract

Dual antiplatelet therapy with aspirin and clopidogrel is effective in limiting adverse coronary thromboischemic events in most patients undergoing coronary stenting. However, platelet reactivity to clopidogrel is variable and stent thrombosis can occur suddenly and unexpectedly in up to 3% of patients. Is responsiveness to clopidogrel an indicator of risk of post-treatment thromboischemic events?

PMID:
19471282
[PubMed - indexed for MEDLINE]
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