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Clin Cancer Res. 2009 Jun 1;15(11):3645-7. doi: 10.1158/1078-0432.CCR-09-0132. Epub 2009 May 26.

Catching cancer by the tail: new perspectives on the use of kinase inhibitors.

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  • 1Center for Cancer Research, Comparative Oncology Program, and Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA.


In this issue of Clinical Cancer Research, London and colleagues evaluate a small molecule multiple-targeted tyrosine kinase inhibitor in dogs with c-kit driven skin cancer. The study represents another example of opportunities to include pet dogs in studies that improve our understanding of human cancer biology and therapy.

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