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    Org Biomol Chem. 2009 Jun 7;7(11):2247-54. Epub 2009 Apr 27.

    New development of glycan arrays.

    Source

    The Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei 115, Taiwan. cyiwu@gate.sinica.edu.tw

    Abstract

    The development of glycan arrays has enabled the high-sensitivity and high-throughput analysis of carbohydrate-protein interactions and contributed to significant advances in glycomics. A number of new array platforms that allow for qualitative and quantitative analysis of mono- and multivalent interactions on surfaces have been developed recently. Glycan arrays are not only a powerful tool for basic research, but also a promising technique for medical diagnosis, and detection of pathogens and cancers. These studies also have led to the design of efficient carbohydrate-based antimicrobial or anticancer vaccines.

    PMID:
    19462030
    [PubMed - indexed for MEDLINE]

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