Display Settings:

Format

Send to:

Choose Destination
Nano Lett. 2009 Jun;9(6):2508-10. doi: 10.1021/nl901398t.

Mitochondrial cristae revealed with focused light.

Author information

  • 1Max Planck Institute for Biophysical Chemistry, Department of NanoBiophotonics, 37077 Gottingen, Germany.

Abstract

Because of the diffraction resolution barrier, optical microscopes have so far failed in visualizing the mitochondrial cristae, that is, the folds of the inner membrane of this 200 to 400 nm diameter sized tubular organelle. Realizing a approximately 30 nm isotropic subdiffraction resolution in isoSTED fluorescence nanoscopy, we have visualized these essential structures in the mitochondria of intact cells. We find a pronounced heterogeneity in the cristae arrangements even within individual mitochondrial tubules.

PMID:
19459703
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Write to the Help Desk