J Neuroophthalmol. 2009 Mar;29(1):13-5.

Restricted diffusion in the optic nerve and retina demonstrated by MRI in rhino-orbital mucormycosis.

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Department of Radiology, Ankara Numune Education and Research Hospital, Ankara, Turkey. gulhatip@yahoo.com

Abstract

A 29-year-old man developed vision loss in the right eye due to ophthalmic artery, cavernous sinus, and superior ophthalmic vein occlusion in mucormycosis. Diffusion MRI obtained within 2 days of symptom onset showed that the apparent diffusion coefficient values of the optic nerve and retina were remarkably decreased on the affected compared with the unaffected side. A follow-up MRI study 21 days after symptom onset revealed the anticipated disappearance of these signal changes, confirming that they were a true reflection of ischemia in the optic nerve and retina. This report adds to an accumulating body of literature on restricted diffusion in these tissues in conditions producing severe ischemia.

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Restricted diffusion in the optic nerve and retina demonstrated by MRI in rhino-orbital mucormycosis.

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