J Autism Dev Disord. 2009 Sep;39(9):1350-8. Epub 2009 May 19.

Evaluation of the ADOS revised algorithm: the applicability in 558 Dutch children and adolescents.

de Bildt A, Sytema S, van Lang ND, Minderaa RB, van Engeland H, de Jonge MV.

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Department of Child and Adolescent Psychiatry, University Medical Centre Groningen, Groningen, The Netherlands. a.de.bildt@accare.nl

Abstract

The revised ADOS algorithms, proposed by Gotham et al. (J Autism Dev Disord 37:613-627, 2007), were investigated in an independent sample of 558 Dutch children (modules 1, 2 and 3). The revised algorithms lead to better balanced sensitivity and specificity for modules 2 and 3, without losing efficiency of the classification. Including the restricted repetitive behaviour domain in the algorithm contributes to a clinical ASD classification in modules 2 and 3. For module 1, the results indicate less improvement, probably due to the low-functioning population. In most groups, the advantages of the revised algorithms are achieved without losing the strength of the original algorithm.

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