Diterpenoids from Casearia sylvestris

Planta Med. 2009 Oct;75(13):1436-41. doi: 10.1055/s-0029-1185726. Epub 2009 May 14.

Abstract

Two highly oxygenated clerodane diterpenes casearins U (1) and V (2) and two ent-kaurane diterpene glucosides sylvestrisides A (3) and B (4) were isolated from the leaves of Casearia sylvestris, together with 13 known compounds. Their structures were established on the basis of 1D and 2D NMR spectroscopic analyses and comparison with literature data.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Casearia / chemistry*
  • Cell Line, Tumor
  • Chlorocebus aethiops
  • Diterpenes / chemistry
  • Diterpenes / isolation & purification*
  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • Humans
  • Molecular Structure
  • Plant Extracts / chemistry*
  • Plant Leaves
  • Vero Cells

Substances

  • Diterpenes
  • Glucosides
  • Plant Extracts
  • casearin U
  • casearin V
  • sylvestriside A
  • sylvestriside B