J Bone Miner Metab. 2009;27(6):733-7. Epub 2009 May 15.

Effect of vitamin D supplementation in the institutionalized elderly.

Himeno M, Tsugawa N, Kuwabara A, Fujii M, Kawai N, Kato Y, Kihara N, Toyoda T, Kishimoto M, Ogawa Y, Kido S, Noike T, Okano T, Tanaka K.

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Department of Food and Nutrition, Kyoto Women's University, Kyoto 605-8501, Japan.

Abstract

An intervention study with vitamin D supplementation was conducted in order to study the amount of vitamin D required in the elderly. Sixty-four institutionalized elderly were randomly assigned to two groups: group (A) to take a beverage containing 200 mg calcium daily, and group (B) to take a beverage containing 200 mg calcium and 5 microg vitamin D daily for 30 days. Prior to the study, the subjects' average vitamin D intake was 7.3 microg/day, which is approximately 150% of the current adequate intake (AI), however their mean plasma 25 OH-D level at baseline was only 12 ng/mL, strongly indicating hypovitaminosis D. During the study, average plasma 25 OH-D concentration significantly increased to 14.7 ng/mL in group (B), but not in group (A). However, group (B) was still in the hypovitaminosis range. Thus, daily intake exceeding the current AI of 5 microg is required for the institutionalized elderly.

PMID:: 19444379; [PubMed - indexed for MEDLINE]

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