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    Photodermatol Photoimmunol Photomed. 2009 Jun;25(3):153-5.

    Low-dose UVA1 phototherapy for proximal and acral scleroderma in systemic sclerosis.

    Rose RF, Turner D, Goodfield MJ, Goulden V.

    Department of Dermatology, The General Infirmary at Leeds, Leeds, UK. beckyrose@doctors.org.uk

    Previous studies report the benefit of UVA1 phototherapy in treating acrosclerosis in patients with systemic sclerosis. We carried out a retrospective study to examine the effectiveness of UVA1 phototherapy in scleroderma affecting acral and proximal sites in patients with this disease. Patients with systemic sclerosis (diffuse type, n=5; limited type, n=3) underwent low-dose UVA1 radiation (30-40 J/cm(2)) thrice weekly. In all patients skin lesions improved, demonstrated by a fall in the modified Rodnan skin score ranging from 8 to 18 points in diffuse systemic sclerosis and 6 to 10 points in limited disease. This study would suggest that UVA1 phototherapy is effective for scleroderma affecting proximal and acral sites in patients with systemic sclerosis.

    PMID: 19438995 [PubMed - indexed for MEDLINE]

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