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J Biol. 2009;8(3):29. doi: 10.1186/jbiol132. Epub 2009 Apr 15.

Reconstructing prokaryotic transcriptional regulatory networks: lessons from actinobacteria.

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  • 1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.

Abstract

Reconstruction of transcriptional regulatory networks of uncharacterized bacteria is a main challenge for the post-genomic era. Recent studies, including one in BMC Systems Biology, address this problem in the relatively underexplored actinobacteria clade, which includes major pathogenic and economically relevant taxa.

PMID:
19435474
[PubMed - indexed for MEDLINE]
PMCID:
PMC2689436
Free PMC Article
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