Send to:

Choose Destination
See comment in PubMed Commons below
Biophys J. 1991 Aug;60(2):433-9.

Estimating the number of channels in patch recordings.

Author information

  • 1Neurosciences Department, Roche Institute of Molecular Biology, Nutley, New Jersey 07110 USA.


The estimation of the number of channels in a patch was assumed to be equivalent to the estimation of the binomial parameter n. Seven estimators were evaluated, using data sets simulated for a range of parameters appropriate for single channel recording experiments. No single estimator was best for all parameters; a combination of estimators is a possible option to avoid the biases of individual estimators. All estimators were highly accurate in estimating n in the case that n = 1. For n </= 4 the simplest estimator, the maximum number of simultaneously open channels, was the best, For larger values of n the best estimators were Bayesian.

Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk