Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
    Physiol Behav. 2009 Apr 20;97(1):87-90. doi: 10.1016/j.physbeh.2009.02.009. Epub 2009 Feb 11.

    Pica as an adaptive response: Kaolin consumption helps rats recover from chemotherapy-induced illness.

    Source

    Monell Chemical Senses Center, 3500 Market St, Philadelphia, PA 19104, USA.

    Abstract

    Clay consumption can occur during illness but there has been little work to understand why. To investigate whether consuming clay confers an advantage to the sick animal, we compared the recovery from illness of adult male rats with or without access to kaolin. Illness was induced by injection of 6 mg/kg, ip, cisplatin, a toxic chemotherapy agent, and recovery was assessed by changes in daily food intake, water intake, and body weight. Relative to saline-injected controls, cisplatin-injected rats reduced food and water intake and lost weight. However, those with access to kaolin ate more food and lost less body weight than did those without access to kaolin. Thus, clay consumption appeared beneficial in that it either protected the rats from illness or enhanced recovery and might prove useful as an adjunct therapy for other animals, including humans, experiencing visceral malaise.

    PMID:
    19419663
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC2680461
    Free PMC Article

    Images from this publication.See all images (1)Free text

    Fig. 1

      Supplemental Content

      Icon for Elsevier Science Icon for PubMed Central

      Save items

      Recent activity

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      Write to the Help Desk