Source
Department of General Practice, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Centre, PO Box 616, 6200 MD Maastricht, Netherlands. j.cals@hag.unimaas.nl
Abstract
OBJECTIVE:
To assess the effect of general practitioner testing for C reactive protein (disease approach) and receiving training in enhanced communication skills (illness approach) on antibiotic prescribing for lower respiratory tract infection.
DESIGN:
Pragmatic, 2x2 factorial, cluster randomised controlled trial.
SETTING:
20 general practices in the Netherlands.
PARTICIPANTS:
40 general practitioners from 20 practices recruited 431 patients with lower respiratory tract infection.
MAIN OUTCOME MEASURES:
The primary outcome was antibiotic prescribing at the index consultation. Secondary outcomes were antibiotic prescribing during 28 days' follow-up, reconsultation, clinical recovery, and patients' satisfaction and enablement.
INTERVENTIONS:
General practitioners' use of C reactive protein point of care testing and training in enhanced communication skills separately and combined, and usual care.
RESULTS:
General practitioners in the C reactive protein test group prescribed antibiotics to 31% of patients compared with 53% in the no test group (P=0.02). General practitioners trained in enhanced communication skills prescribed antibiotics to 27% of patients compared with 54% in the no training group (P<0.01). Both interventions showed a statistically significant effect on antibiotic prescribing at any point during the 28 days' follow-up. Clinicians in the combined intervention group prescribed antibiotics to 23% of patients (interaction term was non-significant). Patients' recovery and satisfaction were similar in all study groups.
CONCLUSION:
Both general practitioners' use of point of care testing for C reactive protein and training in enhanced communication skills significantly reduced antibiotic prescribing for lower respiratory tract infection without compromising patients' recovery and satisfaction with care. A combination of the illness and disease focused approaches may be necessary to achieve the greatest reduction in antibiotic prescribing for this common condition in primary care.
TRIAL REGISTRATION:
Current Controlled Trials ISRCTN85154857.