Format

Send to

Choose Destination
See comment in PubMed Commons below
Curr Gerontol Geriatr Res. 2008:474868. doi: 10.1155/2008/474868. Epub 2008 Sep 1.

Thyroid Function and Cognition during Aging.

Author information

  • 1Research Center on Aging, Health and Social Services Centre, Sherbrooke Geriatrics University Institute, Sherbrooke, Quebec, Canada J1H 4C4.

Abstract

We summarize here the studies examining the association between thyroid function and cognitive performance from an aging perspective. The available data suggest that there may be a continuum in which cognitive dysfunction can result from increased or decreased concentrations of thyroid hormones. Clinical and subclinical hypothyroidism as well as hyperthyroidism in middle-aged and elderly adults are both associated with decreased cognitive functioning, especially memory, visuospatial organization, attention, and reaction time. Mild variations of thyroid function, even within normal limits, can have significant consequences for cognitive function in the elderly. Different cognitive deficits possibly related to thyroid failure do not necessarily follow a consistent pattern, and L-thyroxine treatment may not always completely restore normal functioning in patients with hypothyroidism. There is little or no consensus in the literature regarding how thyroid function is associated with cognitive performance in the elderly.

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Hindawi Publishing Corporation Icon for PubMed Central
    Loading ...
    Write to the Help Desk