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Rev Esp Cardiol. 2009 Apr;62(4):400-8.

Randomized clinical trial of the effectiveness of a home-based intervention in patients with heart failure: the IC-DOM study.

[Article in English, Spanish]

Author information

  • 1Unidad de Investigación, Equipo de Atención Primaria Sardenya, Sardenya 466, Barcelona 08025, Spain. cbrotons@eapsardenya.cat

Abstract

INTRODUCTION AND OBJECTIVES:

The objective of this study was to determine whether a home-based intervention can reduce mortality and hospital readmissions and improve quality of life in patients with heart failure.

METHODS:

A randomized clinical trial was carried out between January 2004 and October 2006. In total, 283 patients admitted to hospital with a diagnosis of heart failure were randomly allocated to a home-based intervention (intervention group) or usual care (control group). The primary end-point was the combination of all-cause mortality and hospital readmission for worsening heart failure at 1-year follow-up.

RESULTS:

The primary end-point was observed in 41.7% of patients in the intervention group and in 54.3% in the control group. The hazard ratio was 0.70 (95% confidence interval [CI] 0.55-0.99). Taking significant clinical variables into account slightly reduced the hazard ratio to 0.62 (95% CI 0.50-0.87). At the end of the study, the quality of life of patients in the intervention group was better than in the control group (18.57 vs. 31.11; P< .001).

CONCLUSIONS:

A home-based intervention for patients with heart failure reduced the aggregate of mortality and hospital readmissions and improved quality of life.

PMID:
19401125
[PubMed - indexed for MEDLINE]
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