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Nat Chem Biol. 2009 Jul;5(7):459-61. doi: 10.1038/nchembio.174.

Green fluorescent proteins are light-induced electron donors.

Author information

  • 1Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.

Abstract

Proteins of the green fluorescent protein (GFP) family are well known owing to their unique biochemistry and extensive use as in vivo markers. We discovered that GFPs of diverse origins can act as light-induced electron donors in photochemical reactions with various electron acceptors, including biologically relevant ones. Moreover, via green-to-red GFP photoconversion, this process can be observed in living cells without additional treatment.

PMID:
19396176
[PubMed - indexed for MEDLINE]
PMCID:
PMC2784199
Free PMC Article
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