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Mult Scler. 2009 May;15(5):644-6. doi: 10.1177/1352458509104590.

Allogeneic mesenchymal stem cells transplantation in treatment of multiple sclerosis.

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  • 1Department of Immunology and Rheumatology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, P. R. China.


Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system. Umbilical cord derived mesenchymal stem cells are immunosuppressive. We transplanted mesenchymal stem cells in a patient with refractory progressive MS, and the disease course was stabilized after the transplantation. We postulate that mesenchymal stem cells have a potent immunosuppressive effect in vivo.

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