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Bioinformatics. 2009 Jun 15;25(12):1552-3. doi: 10.1093/bioinformatics/btp248. Epub 2009 Apr 23.

CROC: finding chromosomal clusters in eukaryotic genomes.

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  • 1Instituto Cavanilles of Biodiversity and Evolutionary Biology, University of Valencia, Apdo, Valencia, Spain. miguel.pignatelli@uv.es



There is increasing evidence showing that co-expression of genes that cluster along the genome is a common characteristic of eukaryotic transcriptomes. Several algorithms have been used to date in the identification of these kinds of gene organization. Here, we present a web tool called CROC that aims to help in the identification and analysis of genomic gene clusters. This method has been successfully used before in the identification of chromosomal clusters in different eukaryotic species.


The web server is freely available to non-commercial users at the following address: http://metagenomics.uv.es/CROC/.

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