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Nat Rev Nephrol. 2009 May;5(5):256-7. doi: 10.1038/nrneph.2009.26.

Acute kidney injury: intravenous fluid to prevent contrast-induced AKI.

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  • 1Veterans Affairs Pittsburgh Healthcare System, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15240, USA.


Trials that compared sodium bicarbonate and sodium chloride for the prevention of contrast-induced acute kidney injury have yielded highly conflicting results. The authors of a recent meta-analysis endeavored to provide a definitive assessment of the relative efficacy of these two intravenous fluids.

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