Clínica Universitária de Dermatologia, Hospital de Santa Maria, Lisboa, Portugal. joaobc77@hotmail.com
We report a case of a man with sarcoidosis and diffuse systemic sclerosis who showed improvement of both diseases after prednisone therapy and remains asymptomatic after three years of follow-up. The association of these two diseases is rare and it is controversial whether this is a chance association or if there is a relationship between the two autoimmune diseases. Despite the poor prognosis and response to therapy of the patients with diffuse systemic sclerosis, our patient had a marked improvement of the disease with prednisone.