[Allergic contact dermatitis to topical drugs: a descriptive analysis]

An Bras Dermatol. 2009 Jan-Feb;84(1):30-4. doi: 10.1590/s0365-05962009000100004.
[Article in Portuguese]

Abstract

Background: Allergic Contact Dermatitis is a common type of dermatitis, but its multiple etiologies hinder its management.

Objective: the objective of this study was to evaluate the frequency of sensitization to topical drugs in a university center, to study the main characteristics of the affected population, and to identify the allergens related with the dermatitis.

Methods: a retrospective and descriptive study with patients submitted to patch tests. The study was conducted with subjects whose patch test to topical drugs was positive.

Results: 329 patients were submitted to patch tests and 42 (13%) had positive and relevant patch tests to topical drugs. Among these patients, 36 (85.7%) had positive patch tests to the principal component and 28 (66.7%) to the other components. Some patients had more than one sensitization. Neomycin was the most important allergen.

Conclusions: Among the studied patients, sensitization to topical agents happened in 13% of the cases, with slight preference for females and Caucasians. There was elevated sensitization to neomycin, a popular agent among patients and medical doctors.

Publication types

  • English Abstract

MeSH terms

  • Administration, Topical
  • Dermatitis, Allergic Contact / epidemiology*
  • Dermatitis, Allergic Contact / etiology*
  • Female
  • Humans
  • Male
  • Retrospective Studies