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Acta Psychiatr Scand. 2009 Aug;120(2):85-96. doi: 10.1111/j.1600-0447.2009.01385.x. Epub 2009 Apr 3.

Prevalence of alcohol use disorders in schizophrenia--a systematic review and meta-analysis.

Author information

  • 1Department of Psychiatry, University of Oulu and Oulu University Hospital, Oulu, Finland. johanna.koskinen@oulu.fi

Abstract

OBJECTIVE:

Our aim was to present recent studies of alcohol use disorders (AUDs) in patients with schizophrenia, estimate overall prevalence and characteristics affecting the prevalence of AUDs.

METHOD:

We conducted a search using three literature databases and a manual search on articles published in 1996-2008. Meta-regression was used to study how prevalence is affected by different study characteristics. Articles that reported diagnoses according to DSM or ICD diagnostic systems were included.

RESULTS:

Altogether 60 studies met our criteria. The median of current AUD prevalence was 9.4% (inter-quartile range, IQR 4.6-19.0, 18 studies) and median of lifetime AUD prevalence 20.6% (IQR 12.0-34.5, 47 studies). In studies using DSM-III-R median prevalence was higher than that in studies using DSM-IV, ICD-9 or ICD-10 (32/17/11/6%).

CONCLUSION:

Approximately every fifth patient with schizophrenia had lifetime AUD diagnosis. When contrasted with the most recent review, there might be a descending trend in AUD prevalence in patients with schizophrenia.

PMID:
19374633
[PubMed - indexed for MEDLINE]
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