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Med Pregl. 2008 Nov-Dec;61(11-12):586-90.

[Specific dermatoses of pregnancy--new classification and differential diagnosis].

[Article in Serbian]

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  • 1Medicinski fakultet Beograd, Katedra za dermatovenerologiju, Klinicki centar Srbije, Beograd, Institut za dermatovenerologiju.

Abstract

INTRODUCTION:

The specific dermatoses of pregnancy represent heterogeneous group of pruritic skin disorders that occur exclusively in pregnancy.

SPECIFIC DERMATOSES OF PREGNANCY:

The updated classification proposed subdividing specific dermatoses of pregnancy into four main categories: 1. atopic eruption of pregnancy; 2. polymorphic eruption of pregnancy; 3. pemphigoid gestationis; 4. intrahepatic cholestasis of pregnancy. Severe pruritius, which is the main symptom in all 4 entities, can impair maternal quality of life. Significant maternal risks are not associated with specific dermatoses of pregnancy; however, pemphigoid gestationis and intrahepatic cholestasis of pregnancy are associated with fetal risks.

CONCLUSION:

Pathognomonic laboratory tests are not available, except direct immunofluorescence which is diagnostic of pemphigoid gestationis and elevated serum level of bile acids of intrahepatic cholestasis of pregnancy. Characteristic clinical features provide discrimination between polymorphic eruption of pregnancy and atopic eruption of pregnancy.

PMID:
19368277
[PubMed - indexed for MEDLINE]
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