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Res Microbiol. 2009 May;160(4):278-87. doi: 10.1016/j.resmic.2009.03.004. Epub 2009 Apr 12.

Multiple target regulation by small noncoding RNAs rewires gene expression at the post-transcriptional level.

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  • 1Max Planck Institute for Infection Biology, RNA Biology Group, Charit├ęplatz 1, 10117 Berlin, Germany.

Abstract

Small noncoding RNAs (sRNAs), often in conjunction with Hfq protein, have increasingly been shown to regulate multiple rather than individual mRNAs, thereby reprogramming gene expression at the post-transcriptional level. This review summarizes how and when several such regulators (CyaR, DsrA, GcvB, OmrAB, RNAIII, RybB, RyhB) act upon multiple targets.

PMID:
19366629
[PubMed - indexed for MEDLINE]
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