Antimicrob Agents Chemother. 2009 Jun;53(6):2616-9. Epub 2009 Apr 13.

Identification of a novel variant of staphylococcal cassette chromosome mec, type II.5, and Its truncated form by insertion of putative conjugative transposon Tn6012.

Han X, Ito T, Takeuchi F, Ma XX, Takasu M, Uehara Y, Oliveira DC, de Lencastre H, Hiramatsu K.

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Department of Infection Control Science, Graduate School of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.

Abstract

We identified two novel staphylococcal cassette chromosome mec (SCCmec) elements in sequence type 8 methicillin-resistant Staphylococcus aureus strains isolated in Japan: type II.5 SCCmec, whose J1 region was highly homologous to that of type I.2 SCCmec of strain PL72 (previously isolated in Poland), and its J1 region variant caused by the deletion/insertion of putative conjugative transposon Tn6012, identified in four S. aureus genomes.

PMID:: 19364875; [PubMed - indexed for MEDLINE]
PMCID:: PMC2687193

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Research Support, Non-U.S. Gov't

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DNA Transposable Elements

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