Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Photodiagnosis Photodyn Ther. 2008 Mar;5(1):19-28. doi: 10.1016/j.pdpdt.2008.02.001. Epub 2008 Mar 4.

Bio-nanotechnology and photodynamic therapy--state of the art review.

Author information

  • 1Brody School of Medicine at ECU, Radiation Oncology, 600 Moye Blvd LJCC172, Greenville, NC 28758, USA.

Abstract

Photodynamic therapy (PDT) and bio-nanotechnology (NT) show striking similarities in clinical design and mechanistics. The PDT paradigm of photosensitizer application, light activation and singlet oxygen generation does in fact occur on the nanoscale level as does the resultant outcomes. NT has the ability to explain as well as modify each of the critical steps of PDT particularly photosensitizer design and delivery, light source miniaturization and optimization, location and intensity of the photodynamic reaction as well as offering a far greater insight into dosimetry and mechanisms of action. This review will explore the current and potential future interactions and modifications NT may have on PDT.

PMID:
19356632
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk