Eur Arch Otorhinolaryngol. 2010 Jan;267(1):117-21.

Evaluation of the revised TNM classification in advanced laryngeal cancer.

Psychogios G, Waldfahrer F, Bozzato A, Iro H.

Source

Department of Otorhinolaryngology Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Waldstrasse 1, 91054 Erlangen, Germany. Georgios.Psychogios@uk-erlangen.de

Abstract

The latest revision of the UICCs TNM classification in 2002 subdivided advanced laryngeal carcinoma into the subcategories T4a and T4b, in order to emphasise the poor prognosis and inoperability of the latter group. Our study aims at evaluating the prognostic relevance of this subclassification. This retrospective analysis includes 163 patients treated for advanced laryngeal carcinoma between 1980 and 2002. The disease-free 5-year-survival rates for patients suffering from T4a and T4b laryngeal carcinoma were 32.4 and 6.7%, respectively (P = 0.003). The T-category and free margins proved to be significant prognostic factors. The survival of patients suffering from T4a carcinoma proved to be independent of specific location and number of invaded structures. This study confirms the much poorer prognosis for patients suffering from T4b carcinoma and thus supports the modified TNM classification.

PMID:: 19350258; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Supplemental Content

Save items

Related citations in PubMed

Prognostic indicators for renal cell carcinoma: a multivariate analysis of 643 patients using the revised 1997 TNM staging criteria. [J Urol. 2000]
Prognostic indicators for renal cell carcinoma: a multivariate analysis of 643 patients using the revised 1997 TNM staging criteria.
Tsui KH, Shvarts O, Smith RB, Figlin RA, deKernion JB, Belldegrun A. J Urol. 2000 Apr; 163(4):1090-5; quiz 1295.
Pathologic staging of renal cell carcinoma: significance of tumor classification with the 1997 TNM staging system. [Cancer. 2001]
Pathologic staging of renal cell carcinoma: significance of tumor classification with the 1997 TNM staging system.
Gettman MT, Blute ML, Spotts B, Bryant SC, Zincke H. Cancer. 2001 Jan 15; 91(2):354-61.
Evaluation of the newly updated TNM classification of head and neck carcinoma with data from 3247 patients. [Cancer. 1998]
Evaluation of the newly updated TNM classification of head and neck carcinoma with data from 3247 patients.
Iro H, Waldfahrer F. Cancer. 1998 Nov 15; 83(10):2201-7.
Review Multicentric and multifocal versus unifocal breast cancer: is the tumor-node-metastasis classification justified? [Breast Cancer Res Treat. 2010]
Review Multicentric and multifocal versus unifocal breast cancer: is the tumor-node-metastasis classification justified?
Weissenbacher TM, Zschage M, Janni W, Jeschke U, Dimpfl T, Mayr D, Rack B, Schindlbeck C, Friese K, Dian D. Breast Cancer Res Treat. 2010 Jul; 122(1):27-34. Epub 2010 May 8.
Review Confusion by frequent changes in staging of exocrine pancreatic carcinoma. [Pancreas. 2004]
Review Confusion by frequent changes in staging of exocrine pancreatic carcinoma.
Merkel S, Mansmann U, Meyer T, Papadopoulos T, Hohenberger W, Hermanek P. Pancreas. 2004 Oct; 29(3):171-8.

See reviews... See all...

Recent activity

Clear Turn Off Turn On

Evaluation of the revised TNM classification in advanced laryngeal cancer.
Evaluation of the revised TNM classification in advanced laryngeal cancer.
Eur Arch Otorhinolaryngol. 2010 Jan ;267(1):117-21.

PubMed
Electroconvulsive therapy in the treatment of depression: the impact on length o...
Electroconvulsive therapy in the treatment of depression: the impact on length of stay.
Compr Psychiatry. 1991 Jul-Aug ;32(4):345-54.

PubMed
Correlates of hopelessness in psychiatrically hospitalized children.
Correlates of hopelessness in psychiatrically hospitalized children.
Compr Psychiatry. 1991 Jul-Aug ;32(4):330-7.

PubMed
Spinal cord hyperexcitability and its role in pain and hyperalgesia.
Spinal cord hyperexcitability and its role in pain and hyperalgesia.
Exp Brain Res. 2009 Jun ;196(1):129-37. Epub 2009 Apr 7 .

PubMed
Occurrence of delirium is severely underestimated in the ICU during daily care.
Occurrence of delirium is severely underestimated in the ICU during daily care.
Intensive Care Med. 2009 Jul ;35(7):1276-80. Epub 2009 Apr 7 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Evaluation of the revised TNM classification in advanced laryngeal cancer.

Source

Abstract

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information