Abstract
Pattern of events: A simple and flexible method has been developed for patterning cell adhesion ligands. Locally erasing self-assembled monolayers with tri(ethyleneglycol) groups on a gold substrate by using a MALDI-TOF MS nitrogen laser and filling the exposed gold surface with an alkanethiol presenting carboxylic acid groups enables subsequent immobilization of maleimide and a cell adhesion peptide, which can then recognize cells (see scheme).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Adhesion Molecules / chemistry*
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Cell Adhesion*
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Ethylene Glycols / chemistry
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Gold / chemistry
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Immobilized Proteins / chemistry*
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Ligands
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Maleimides / chemistry
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Oligopeptides / chemistry*
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Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods*
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Surface Properties
Substances
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Cell Adhesion Molecules
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Ethylene Glycols
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Immobilized Proteins
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Ligands
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Maleimides
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Oligopeptides
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maleimide
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Gold