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Nat Rev Neurol. 2009 Apr;5(4):182-3. doi: 10.1038/nrneurol.2009.31.

MRI--the perfect surrogate marker for multiple sclerosis?

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  • 1MS Center Amsterdam and Department of Radiology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands. f.barkhof@vumc.nl

Abstract

MRI provides a very sensitive reflection of the histopathological changes in multiple sclerosis. Many short-term studies fail to appreciate the relationship between MRI and clinical findings, although such shortcomings might be argued to reflect a weakness of clinical measures, rather than of MRI.

PMID:
19347020
[PubMed - indexed for MEDLINE]
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