Anticancer Drugs. 2009 Jan;20(1):75-8.

Alpha-fetoprotein expressing metastastic adenocarcinoma of the esophago-gastric junction responding favorably to capecitabine and oxaliplatin.

Kripp M, Ströbel P, Dinter D, Lukan N, Hochhaus A, Hofheinz RD.

Source

Onkologisches Zentrum, III. Medizinische Klinik, Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Germany. melanie.kripp@med3.ma.uni-heidelberg.de

Abstract

Alpha-fetoprotein-producing metastatic adenocarcinoma of the stomach or the esophago-gastric junction usually exhibits either no or only short-term remission while receiving palliative chemotherapy. We report on a 76-year-old male patient suffering from an unresectable alpha-fetoprotein-producing adenocarcinoma of the esophago-gastric junction with several liver metastases. He was treated with capecitabine and oxaliplatin-based combination therapy. A long-lasting major remission was observed resulting in a survival of 18.5 months.

PMID:: 19343004; [PubMed - indexed for MEDLINE]

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