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    J Subst Abuse Treat. 2009 Oct;37(3):247-55. Epub 2009 Mar 31.

    Comparing smoking treatment programs for lighter smokers with and without a history of heavier smoking.

    Gariti P, Lynch K, Alterman A, Kampman K, Xie H, Varillo K.

    Department of Psychiatry, Center for the Study of Addictions, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. gariti_p@mail.trc.upenn.edu

    The study examined the impact of counseling intensity (high vs. low) combined with either bupropion or the nicotine patch. Two hundred sixty participants smoking 6 to 15 cigarettes per day (cpd) were enrolled in a year-long study to examine the effects of treatment. Four groups of smokers under medication-blinded conditions were compared for treatment completion and abstinence at three follow-up points from the initiation of treatment (Weeks 12, 26, and 52). Both counseling groups had similar treatment completion rates (i.e., defined by a combination of counseling attendance and medication adherence levels). There was a main treatment effect for abstinence favoring the high counseling condition in early follow-up (Week 12) and for continuous abstinence. Participants with a history of heavier smoking (> or =20 cpd) and African American smokers were least likely to be smoke free at the end of the study. The study has implications for identifying the treatment needs of lighter smokers.

    PMID: 19339135 [PubMed - indexed for MEDLINE]

    PMCID: 2778325

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    • Bupropion (Aplenzin®, Wellbutrin®, Wellbutrin® SR, ...)

      Bupropion (Aplenzin, Wellbutrin, Wellbutrin SR, Wellbutrin XL) is used to treat depression. Bupropion (Wellbutrin XL) is also used to treat seasonal affective disorder (SAD; episodes of depression that occur in the fall ...

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