Clin Vaccine Immunol. 2009 May;16(5):772-4. Epub 2009 Mar 25.

Good performance of immunoglobulin M assays in diagnosing genotype 3 hepatitis E virus infections.

Legrand-Abravanel F, Thevenet I, Mansuy JM, Saune K, Vischi F, Peron JM, Kamar N, Rostaing L, Izopet J.

Source

Laboratoire de Virologie, Institut Fédératif de Biologie, TSA 40031, CHU Toulouse Purpan, Toulouse Cedex, France.

Abstract

We have evaluated three anti-hepatitis E virus (anti-HEV) immunoglobulin M (IgM) assays, the EIAgen HEV IgM assay (Adaltis), the HEV IgM enzyme-linked immunosorbent assay 3.0, and the Assure HEV IgM rapid test (MP Diagnostics), for the routine detection of acute genotype 3 HEV. Their sensitivities were fairly good (90%, 88%, and 82%), and their specificities were excellent (100%, 99.5%, and 100%).

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Cited by 6 PubMed Central articles

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