Arthritis Rheum. 1991 Oct;34(10):1329-31.

Allopurinol sensitivity in a patient with chronic tophaceous gout: success of intravenous desensitization after failure of oral desensitization.

Walz-LeBlanc BA, Reynolds WJ, MacFadden DK.

Source

Toronto Hospital Arthritis Centre, Ontario, Canada.

Erratum in

Arthritis Rheum 1992 Jan;35(1):125.

Abstract

Sensitivity to allopurinol, which occurs in 10-15% of patients, can seriously limit the drug's use in chronic tophaceous gout. Oral allopurinol desensitization has been advocated for sensitive patients in whom use of the drug is warranted. We report the successful use of intravenous allopurinol desensitization in a patient with chronic tophaceous gout in whom oral desensitization had previously failed.

Comment in

Arthritis Rheum. 1992 Jul;35(7):842-3.

PMID:: 1930322; [PubMed - indexed for MEDLINE]

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