Isolation of notoamide E, a key precursor in the biosynthesis of prenylated indole alkaloids in a marine-derived fungus, Aspergillus sp

J Am Chem Soc. 2009 Mar 25;131(11):3834-5. doi: 10.1021/ja810029b.

Abstract

Notoamide E was identified to be a short-lived precursor in the biosynthesis of prenylated indole alkaloids in the mussel-derived Aspergillus sp. In addition, the feeding experiment of the (13)C-labeled notoamide E afforded structurally novel metabolites.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Aspergillus / chemistry*
  • Aspergillus / metabolism
  • Bivalvia / microbiology
  • Carbon Isotopes / metabolism
  • Indole Alkaloids / isolation & purification*
  • Indole Alkaloids / metabolism
  • Prenylation

Substances

  • Carbon Isotopes
  • Indole Alkaloids
  • notoamide E