Format

Send to:

Choose Destination
See comment in PubMed Commons below
Nephron Clin Pract. 2009;111(4):c223-8. doi: 10.1159/000208990. Epub 2009 Mar 14.

Tripterygium wilfordii Hook F treatment for idiopathic refractory nephrotic syndrome in adults: a meta-analysis.

Author information

  • 1Department of Nephrology, Second Affiliated Hospital, Nanchang University, No. 1 Minde Road, Nanchang, PR China. xugaosi@gmail.com

Abstract

Tripterygium wilfordii Hook F (TwHF) is a Chinese herbal medicine with immunosuppressive effects and an established history of use in the treatment of inflammatory and autoimmune diseases. We have carried out a meta-analysis of randomized controlled trials (RCTs) and quasi-RCTs which assessed the effectiveness of TwHF in the treatment for idiopathic refractory nephrotic syndrome (IRNS). After reading the full text, only three RCTs or quasi-RCTs meeting our inclusion criteria were selected. Our meta-analysis indicated that TwHF has beneficial effects on the remission of IRNS. There was no significant publication bias in the meta-analysis studies. However, studies with a larger sample size and including patients with both a mild and severe histopathological change involvement separately are needed to assess the effects of TwHF in IRNS patients before exact conclusions can be drawn.

Copyright (c) 2009 S. Karger AG, Basel.

PMID:
19287181
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for S. Karger AG, Basel, Switzerland Icon for PubMed Health
    Loading ...
    Write to the Help Desk