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Genome Biol. 2009;10(3):R29. doi: 10.1186/gb-2009-10-3-r29. Epub 2009 Mar 12.

TFCat: the curated catalog of mouse and human transcription factors.

Author information

  • 1Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada. debra@cmmt.ubc.ca


Unravelling regulatory programs governed by transcription factors (TFs) is fundamental to understanding biological systems. TFCat is a catalog of mouse and human TFs based on a reliable core collection of annotations obtained by expert review of the scientific literature. The collection, including proven and homology-based candidate TFs, is annotated within a function-based taxonomy and DNA-binding proteins are organized within a classification system. All data and user-feedback mechanisms are available at the TFCat portal (http://www.tfcat.ca).

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