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Presse Med. 2009 May;38(5):799-807. doi: 10.1016/j.lpm.2009.01.012. Epub 2009 Mar 10.

[Indications of anakinra].

[Article in French]

Author information

  • 1Service de rhumatologie, GH Pitié-Salpêtrière, AP-HP, Université Paris 6 Pierre et Marie Curie, UFR de médecine, Site Pitié-Salpêtrière, F-75013 Paris, France.


The efficacy of anakinra on both RA-related symptoms and structural damage has been demonstrated in several randomized controlled trials. However, its interest seems limited with regards to other biologic agents. Anakinra seems promising in the treatment of childhood or adult onset Still disease, after the failure of both high dose steroids and methotrexate. The efficacy of anakinra is dramatic in several hereditary auto-inflammatory syndromes. Anakinra could be an interesting drug for the treatment of neutrophilic dermatosis or relapsing chondritis, refractory to conventional agents. Injection site reactions and infections are the 2 main anakinra-related side effects.

[PubMed - indexed for MEDLINE]
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