Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 May;107(5):685-90. doi: 10.1016/j.tripleo.2008.12.046. Epub 2009 Mar 9.

    Vascular solitary fibrous tumor with "floret" cells or giant cell angiofibroma? A lingual example highlighting the overlapping characteristics of these entities and positive immunoreaction for estrogen and progesterone receptors.

    Source

    Department of Oral Pathology and Oral Medicine, Dental School, National and Kapodistrian University of Athens, Athens, Greece.

    Abstract

    Recent literature suggests that giant cell angiofibroma (GCAF) is a variant of solitary fibrous tumor (SFT) and not just a related lesion. Herein we present a case of apparent SFT with giant cells, including floret cells and focal pseudovascular areas, which are defining features of GCAF. The tumor occurred in the tongue of an 84-year-old female and depicted an encapsulated, patternless spindle cell proliferation in a fibromyxoid stroma with focal dense collagenous areas and scattered floret-type multinucleated giant cells seen primarily in the periphery, as well as pseudovascular spaces, numerous capillaries, and hemangiopericytomalike areas. Immunohistochemical investigation revealed positive staining for CD34 and positive immunoreaction for estrogen and progesterone receptors. We support the present notion that GCAF is a histologic subtype of SFT.

    PMID:
    19272802
    [PubMed - indexed for MEDLINE]

      Supplemental Content

      Icon for Elsevier Science

      Save items

      Recent activity

      • Vascular solitary fibrous tumor with "floret" cells or giant cell angiofibroma? ...
        Vascular solitary fibrous tumor with "floret" cells or giant cell angiofibroma? A lingual example highlighting the overlapping characteristics of these entities and positive immunoreaction for estrogen and progesterone receptors.
        Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 May ;107(5):685-90. doi: 10.1016/j.tripleo.2008.12.046. Epub 2009 Mar 9 .
        PubMed

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      Write to the Help Desk