Send to:

Choose Destination
See comment in PubMed Commons below
Environ Health Perspect. 2009 Feb;117(2):167-74. doi: 10.1289/ehp.11543. Epub 2008 Sep 15.

Particulate matter (PM) research centers (1999-2005) and the role of interdisciplinary center-based research.

Author information

  • 1Center for Environmental and Occupational Health, School of Public Health, University of California at Los Angeles, Los Angeles, California 90095, USA.



The U.S. Environmental Protection Agency funded five academic centers in 1999 to address the uncertainties in exposure, toxicity, and health effects of airborne particulate matter (PM) identified in the "Research Priorities for Airborne Particulate Matter" of the National Research Council (NRC). The centers were structured to promote interdisciplinary approaches to address research priorities of the NRC. In this report, we present selected accomplishments from the first 6 years of the PM Centers, with a focus on the advantages afforded by the interdisciplinary, center-based research approach. The review highlights advances in the area of ultrafine particles and traffic-related health effects as well as cardiovascular and respiratory effects, mechanisms, susceptibility, and PM exposure and characterization issues.


The collective publications of the centers served as the data source. To provide a concise synthesis of overall findings, authors representing each of the five centers identified a limited number of topic areas that serve to illustrate the key accomplishments of the PM Centers program, and a consensus statement was developed.


The PM Centers program has effectively applied interdisciplinary research approaches to advance PM science.


acute effects; biological mechanisms; chronic effects; criteria pollutants; dosimetry; exposure assessment; morbidity; mortality; particulate matter

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for National Institute of Environmental Health Sciences Icon for PubMed Central
    Loading ...
    Write to the Help Desk