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Am J Gastroenterol. 2009 Mar;104 Suppl 2:S10-6. doi: 10.1038/ajg.2009.46.

Proton pump inhibitor use and enteric infections.

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  • 1Department of Medicine, Montreal Chest Institute and SMBD-Jewish General Hospital, McGill University, Montreal, Quebec, Canada.


Proton pump inhibitors (PPIs) and H2 receptor antagonists (H2RAs) are very commonly prescribed drugs and are routinely used in the chronic management of gastro-esophageal reflux disease. Concerns have been raised about the possible association of PPIs with enteric infections. This article reviews the studies that have examined the associations of proton pump inhibitors in particular, and enteric infections.

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