Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Bioinformatics. 2009 May 1;25(9):1211-3. doi: 10.1093/bioinformatics/btp124. Epub 2009 Mar 4.

SpliceAid: a database of experimental RNA target motifs bound by splicing proteins in humans.

Author information

  • 1Institute of Biology and Genetics, Polytechnic University of Marche, 60131, Ancona, Italy. f.piva@univpm.it

Abstract

The correct post-transcriptional RNA processing is finely regulated by RNA-binding proteins. Unfortunately, there is little experimental information on target RNA sequences of RNA-binding proteins and moreover such experimentally derived target sequences are annotated in a compact form by the score matrices that overestimate the number of possible recognized sequences. We carried out an exhaustive hand curated literature search to create a database, SpliceAid, collecting all the experimentally assessed target RNA sequences that are bound by splicing proteins in humans. We built a web resource, database driven, to easy query SpliceAid and give back the results by an accurate and dynamic graphic representation.

AVAILABILITY:

SpliceAid database is freely accessible at http://www.introni.it/splicing.html.

PMID:
19261717
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk