Send to:

Choose Destination
See comment in PubMed Commons below
Microbiol Mol Biol Rev. 2009 Mar;73(1):62-70. doi: 10.1128/MMBR.00028-08.

Environmental proteomics: a paradigm shift in characterizing microbial activities at the molecular level.

Author information

  • 1Biosciences Division, Oak Ridge National Laboratory, One Bethel Valley Road, P.O. Box 2008, MS-6026, Oak Ridge, TN 37831, USA.


The increase in sequencing capacity led to a new wave of metagenomic projects, enabling and setting the prerequisite for the application of environmental proteomics technologies. This review describes the current status of environmental proteomics. It describes sample preparation as well as the two major technologies applied within this field: two-dimensional electrophoresis-based environmental proteomics and liquid chromatography-mass spectrometry-based environmental proteomics. It also highlights current publications and describes major scientific findings. The review closes with a discussion of critical improvements in the area of integrating experimental mass spectrometry technologies with bioinformatics as well as improved sample handling.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk