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Nat Cell Biol. 2009 Mar;11(3):243-5. doi: 10.1038/ncb0309-243.

How to grow a bud: an importin acts in asymmetric division.

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  • 1Department of Biology, University of Rochester, Rochester, NY 14627, USA.


The growth of daughter cells in budding yeast is a classic model for investigating mechanisms involved in asymmetric cell division. An unexpected collaboration between the DEAD-box protein Dbp5 and the nuclear transport receptor Kap104 controls localized protein synthesis at the bud tip during mitosis.

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